Study Finds Childhood Trauma Can Make People Like Morphine More

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Last Updated on August 27, 2026

Studies have indicated that there are high rates of childhood trauma among people with addictions. Now, recent research findings have revealed more insight into the impact of these experiences and their effects on addictive behaviors.

Researchers at the University of Exter have discovered that people who have experienced childhood trauma get a more pleasurable “high” from morphine. Now, the scientists who made this recent discovery compared the effects of morphine on 52 healthy people: 27 with a history of childhood abuse and neglect, and 25 who reported no such experiences in childhood.1

According to the study, those who reported having childhood trauma liked the morphine more, felt more euphoric side effects, and had a stronger desire for a second dose. Comparatively, those without traumatic childhood experiences were more likely to dislike the effects of morphine and feel nauseous or dizzy.

Related blog: Alcohol Abuse Has Increased During the COVID-19 Pandemic, According to Study

Why do traumatic childhood experiences affect responses to morphine?

Understandably, one thing you might be wondering is why traumatic childhood experiences cause this type of sensitivity to the pleasurable effects of opioids. While there is no definitive explanation yet, the researchers that conducted the study do have one possible explanation.

For example, according to the study from the University of Exter, childhood trauma may negatively influence the development of a pain-relieving system called the endogenous opioid system. This system is found throughout the central nervous system in the body and is sensitive to endorphins, which are natural opioids produced by our bodies.

To explain further, when babies are comforted in infancy, such as when they cry, their bodies produce endorphins. But, when their emotional needs go unmet, their endogenous opioid system may develop differently. As a result, it could become more sensitive to the euphoric and rewarding effects of opioids. Consequently, these developmental differences could be the key to understanding the link between childhood trauma and its link to the effects of opioids.

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Why is this study important?

Most importantly, the lead author who conducted the study, Dr Molly Carlyle, said this may be the first study that links childhood trauma with the effects of opioids in people who don’t have a history of addiction. The findings suggest that people who have experienced childhood trauma may be more sensitive to the pleasurable effects of opioids. As a result, it may help reduce the stigma of heroin addiction.

Far too often, heroin addiction is treated as though it’s a personal weakness or a moral failing and that people who struggle with it simply lack self-control. However, the findings of this study emphasize the fact that we should be treating people with opioid addiction with more compassion, just like we would treat other survivors of childhood trauma.

Receive compassionate treatment for addiction at Nova Recovery Center

To sum things up, regardless of who you are or what type of history you’ve had, at Nova Recovery Center, you can expect to receive the highest quality professional addiction treatment from compassionate staff members. We understand what you’re going through and we know how to help you achieve long-lasting sobriety.

Furthermore, we offer a variety of addiction treatment programs to meet you where you are and address your needs. Our staff can help you determine which program(s) would be most helpful for your current situation:

If you’re ready to get help for your addiction, we are available to speak with you now. Please call (512) 605-2955 or contact us online to get started.

References:

  1. https://www.sciencedaily.com/releases/2021/06/210622123224.htm

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Nova Recovery Center is dedicated to helping you or your loved one get help. Please call or fill out this form for a confidential consultation. One of our understanding, dedicated advisors will contact you about your options. Begin healing today.

Clinical Implications: What This Research Means for Addiction Recovery

The link between childhood trauma and opioid sensitivity has significant implications for how addiction treatment is approached at Nova Recovery Center. Understanding that trauma can alter neurobiological responses to substances helps clinicians identify risk factors early and tailor treatment plans with greater precision.

When individuals with trauma histories enter treatment, evidence-based approaches like trauma-informed cognitive behavioral therapy (CBT) and dual-diagnosis care become essential. By addressing both the underlying trauma and the addiction simultaneously, patients have a better foundation for lasting recovery. This research underscores why Nova’s clinical teams assess trauma history as part of the comprehensive intake process.

Key clinical takeaways:

  • Childhood trauma can increase neurobiological vulnerability to opioid dependence, making early intervention critical
  • Trauma-informed treatment recognizes this connection and reduces shame, improving therapeutic engagement
  • Comprehensive assessment of trauma history helps predict treatment response and relapse risk
  • Integrated treatment addressing both trauma and addiction yields better long-term outcomes than treating either in isolation

If you or a loved one has experienced trauma and is struggling with substance use, professional assessment can help clarify the relationship between these experiences and current challenges. Nova Recovery Center’s clinical team is trained in trauma-informed care and can develop a personalized treatment plan that addresses both issues.

Frequently Asked Questions

Does childhood trauma always lead to addiction?

No. While this research shows that trauma can increase biological sensitivity to opioids, many people with trauma histories do not develop addiction. Genetics, environment, access to support, and coping skills all play important roles. Trauma is a risk factor, not a guarantee.

How does trauma-informed care differ from standard addiction treatment?

Trauma-informed care recognizes that trauma has occurred, understands its effects on brain and behavior, and integrates this knowledge into every aspect of treatment. It emphasizes safety, trustworthiness, collaboration, and empowerment—reducing re-traumatization and improving outcomes.

Can people recover from addiction if they haven’t addressed their trauma?

Recovery is possible, but addressing trauma significantly improves the chances of sustained sobriety. Untreated trauma can be a relapse trigger. Comprehensive treatment that tackles both issues simultaneously offers the strongest foundation for long-term recovery.

What treatment options does Nova Recovery Center offer for trauma and addiction?

Nova offers evidence-based approaches including cognitive behavioral therapy (CBT), dynamic family therapy, and trauma-informed counseling. These are available through inpatient residential programs in Austin and Wimberley, Texas, as well as outpatient and online intensive outpatient (IOP) programs across multiple locations.

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Dr. Robert Ulrich

Dr. Robert Ulrich

Medical Director | Nova Recovery Center

Dr. Robert Ulrich serves as Medical Director at Nova Recovery Center, bringing more than two decades of clinical neurology experience to the treatment of substance use disorders. He is board-certified in neurology by the American Board of Psychiatry and Neurology and completed his neurology residency at UT Southwestern Medical Center in Dallas, where he served as Chief Resident.

Throughout his career in neurology, Dr. Ulrich observed that many patients with neurological conditions also faced challenges related to substance use. In late 2022, he shifted his clinical focus toward addiction medicine, applying his extensive knowledge of brain function, neurochemistry, and the central nervous system to support individuals in recovery.

As Medical Director, Dr. Ulrich provides clinical leadership and helps guide the medical services delivered at Nova Recovery Center. His background in neurology allows him to approach addiction treatment with a detailed understanding of the neurological, physical, and behavioral factors that influence substance use and recovery.

Dr. Ulrich works closely with the clinical team to support individualized, evidence-based treatment plans designed to promote patient safety, stability, and long-term recovery.

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