Genealogy and epigenetics both play a substantial role in a person’s relationship with addiction. Researchers are discovering that the age-old saying “nature versus nurture” is more accurately “nature and nurture.” The two concepts work simultaneously to create who we are as people both consciously and on a molecular level. Generational addiction and epigenetics not only account for proclivities people are born with but proclivities towards substance use that people develop in their upbringing. An individual may be predisposed to addiction at birth or it may be ingrained in them through their environment or how they were raised. Let’s discuss how these two concepts relate to addiction—sometimes in tandem.