Effexor Addiction: Side Effects, Detox, Withdrawal, and Treatment Table of Contents Key takeaways Effexor (venlafaxine) withdrawal—also called antidepressant discontinuation syndrome—often begins within 1–3 days of dose reduction or stopping, can peak in the first 1–2 weeks, and usually improves within 3–4 weeks, though some people need longer. A doctor‑guided, gradual taper is the safest approach. … Continue reading Effexor Withdrawal Symptoms: What to Expect & Do